منابع مشابه
Interferon Alfa-2b Therapy in Mucocutaneous Manifestations of Behçet’s Disease
Background: Viral infections such as Epstein-Barr virus and Herpes simplex virus may play a role in the pathogenesis of Behçet’s disease (BD). Interferons (INF) are natural defense mechanisms against viruses and inhibit their activities by enhancing major histocompatibility complex class I and cytokine expression. This study evaluated the efficacy of INF-α-2b on mucocutaneous lesions of BD. Met...
متن کاملInterferon alfa-2b in mixed cryoglobulinaemia: a controlled crossover trial.
To confirm the positive results of a preliminary trial, 26 patients with mixed cryoglobulinaemia were enrolled in a controlled, randomised, crossover trial with interferon alfa-2b. A significant improvement was seen in the purpura score and alanine aminotransferase activities during six months' treatment, and was associated with a significant decrease in cryocrit and a returning to normal of th...
متن کاملinterferon alfa-2b therapy in mucocutaneous manifestations of behçet’s disease
background: viral infections such as epstein-barr virus and herpes simplex virus may play a role in the pathogenesis of behçet’s disease (bd). interferons (inf) are natural defense mechanisms against viruses and inhibit their activities by enhancing major histocompatibility complex class i and cytokine expression. this study evaluated the efficacy of inf-α-2b on mucocutaneous lesions of bd. m...
متن کاملTreatment of acute hepatitis C with interferon alfa-2b.
BACKGROUND In people who are infected with the hepatitis C virus (HCV) chronic infection often develops and is difficult to eradicate. We sought to determine whether treatment during the acute phase could prevent the development of chronic infection. METHODS Between 1998 and 2001, we identified 44 patients throughout Germany who had acute hepatitis C. Patients received 5 million U of interfer...
متن کاملPeginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for treatment of HIV/HCV co-infected patients.
BACKGROUND Current therapies for chronic hepatitis C virus (HCV) in HIV co-infected patients have a low success rate and are poorly tolerated. We have evaluated the efficacy and safety of interferon alfa-2b (IFN) + ribavirin (RBV) versus pegylated interferon alfa-2b (PEG-INF) + RBV. METHODS Randomized, single-centre, open-label clinical trial including patients with: detectable HCV-RNA, alani...
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ژورنال
عنوان ژورنال: InFo Onkologie
سال: 2017
ISSN: 1613-3633,2196-5692
DOI: 10.1007/s15004-017-5899-x